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Prof.Dr. MAYDA GÜRSEL
FACULTY OF ARTS AND SCIENCES
PublicationsResearchMembership & Awards
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Phone :  +90312210 5165
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Education

  Bachelor's, Middle East Technical University, Biological Sciences
  Master's, Middle East Technical University, Biological Sciences
  Doctorate, University of London, Biological Sciences

Publications (INTERNATIONAL)

Journal Papers

  A.1 Yagci FC, Aslan O, Gursel M, Tincer G, Ozdamar Y, Karatepe K, Akcali KC, Gursel, Mammalian telomeric DNA suppresses endotoxin-induced uveitis. "J.Biol.Chem.", 285, (2010), p.28806-11.
  A.2 Erikci E, Gursel M., Gursel I., Differential immune activation following encapsulation of immunostimulatory CpG oligodeoxynucleotide in nanoliposomes. "Biomaterials", 32, (2011), p.1715-1723.
  A.3 Steinhagen F, Meyer C, Tross D, Gursel M, Maeda T, Klaschik S, Klinman DM, Activation of type I interferon-dependent genes characterizes the "core response" induced by CpG DNA.. "Journal of Leukocyte Biology", 92, (2012), p.775-785.
  A.4 Enayat S, Ceyhan MS, Başaran AA, Gürsel M, Banerjee S., Anticarcinogenic Effects of the Ethanolic Extract of Salix aegyptiaca in Colon Cancer Cells: Involvement of Akt/PKB and MAPK Pathways.. "Nutr Cancer", 65, (2013), p.1045-1058.
  A.5 Gursel M, Klinman DM, Gursel I., Plasmacytoid dendritic cell response to CpG ODN correlates with CXCL16 expression and is inhibited by ox-LDL.. "Mediators Inflamm.", 2013, (2013), p.312590.
  A.6 Gungor B, Yagci FC, Gursel I, Gursel M., Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings.. "Oncoimmunology.", 3, (2014).
  A.7 Gungor B, Yagci, Tincer, Bayyurt, Alpdundar, Yildiz, Ozcan, Gursel I, Gursel M, CpG ODN nanorings induce IFNα from plasmacytoid dendritic cells and demonstrate potent vaccine adjuvant activity.. "Sci Transl Med.", 6, (2014).
  A.8 Yildiz S, Alpdundar E, Gungor B, Kahraman T, Bayyurt B, Gursel I, Gursel M., Enhanced immunostimulatory activity of cyclic dinucleotides on mouse cells when complexed with a cell-penetrating peptide or combined with CpG.. "European Journal of Immunology", 45, (2015), p.1170-9.
  A.9 Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casa, Biological properties of extracellular vesicles and their physiological functions.. "Journal of Extracellular Vesicles", 14, (2015).
  A.10 Gungor B, Adiguzel E, Gursel I, Yilmaz B, Gursel M., Intestinal Microbiota in Patients with Spinal Cord Injury.. "Plos One", 11, (2016), p.e0145878.
  A.11 Gursel M, Gursel I., Development of CpG ODN Based Vaccine Adjuvant Formulations.. "Methods Mol Biol.", 1404, (2016).
  A.12 Gucluler G, Adiguzel E, Gungor B, Kahraman T, Gursel M, Yilmaz B, Gursel I., Impaired toll like receptor-7 and 9 induced immune activation in chronic spinal cord injured patients contributes to immune dysfunction.. "Plos One", 12, (2017), p.e0171003.
  A.13 Gul E, Sayar EH, Gungor B, Eroglu FK, Surucu N, Keles S, Guner SN, Fındık S,, Type I IFN related NETosis in Ataxia Telangiectasia and Artemis deficiency.. "J Allergy Clin Immunol.", pii: S009, (2017).
  A.14 Bayyurt B, Tincer G, Almacioglu K, Alpdundar E, Gursel M, Gursel I., Encapsulation of two different TLR ligands into liposomes confer protective immunity and prevent tumor development. "J Control Release", 247, (2017), p.134-144.
  A.15 Kahraman T, Gucluler G, Simsek I, Yagci FC, Yildirim M, Ozen C, Dinc A, Gurse, Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behçet's disease severity. "J Extracell Vesicles", 6, (2017), p.1284449.
 

Conference Papers

  A.1 G. Tincer, M. Sahin, C. Coban, K. Ishii, M. Gursel, İ. Gursel., Polysaccharide-TLR agonist nanocomplexes: Mechanism of action as immune adjuvants. "17. International Symposium on Biomedical Science and Technology", (2011).
  A.2 T. Kahraman, D. Azkur, C. Ozcan, C. N. Kocabas, M. Gursel, I. Gursel., Relationship between Level of Plasma Microparticles and the Clinical Manifestation of Allergic Diseases. "30th EAACI Congress", (2011).
  A.3 B. Gungor, F.C. Yagci, G. Tincer, E. Alpdundar, S. Yildiz, I. Gursel, M. Gursel, Determination of Immune Stimulatory Properties of Synthetic CpG ODN/ Cationic Peptide Complexes. "17. International Symposium on Biomedical Science and Technology", (2011).
  A.4 T. Kahraman, G. Gucluler, E. Alpdundar, M. Gursel, I. Gursel., Encapsulating CpG-ODNs into nanovesicles enhances their immunostimulatory action. "17. International Symposium on Biomedical Science and Technology", (2011).
  A.5 B. Gungor, F.C. Yagci, G. Tincer, E. Alpdundar, S. Yildiz, I. Gursel, M. Gursel, Immunostimulatory Properties of CpG ODN Based Nanoparticles. "17. International Symposium on Biomedical Science and Technology", (2011).
  A.6 Alpdundar E, Yildiz S, Bayyurt B, Ozcan M, Gucluler G, Bayik D, Gungor B, Gursel, Commensal bacteria-derived membrane vesicles supress Th-1 dominated immune responses in vaccinated and tumor-bearing mice.. "15th International Congress of Immunology", (2013).
  A.7 Gungor B, Yagcı F, Gursel I and Gursel M., CpG Oligodeoxynucleotide/cationic peptide nanorings as immunotherapeutic agents.. "", (2013).
  A.8 Yildiz S, Alpdundar E, Bayyurt B, Ozcan M, Gucluler G, Bayik D, Gungor B, Gursel, Cyclic-di-GMP based immune stimulatory formulations as novel vaccine adjuvants and anti-cancer agents.. "", (2013).
  A.9 M.M. Aydin, E. Alpdundar, M. Gursel, K.C. Akcali, REVERSING THE PROGRESS OF LIVER FIBROSIS USING MEMBRANE VESICLES SECRETED FROM COMMENSAL BACTERIA. "Journal of Hepatology", 60, (2014).
  A.10 Gul, E.; Eroglu, Kara F.; Surucu, N. Yakicier C, Gursel I. Ozen S. Gursel M, Type I interferon associated immune responses In STING associated vasculopathy with onset in infancy (SAVI) patients. "EUROPEAN JOURNAL OF IMMUNOLOGY", 46, (2016).
  A.11 B. Gungor, I.C. Ayanoglu, H. Taşkıran, G. Tincer Konig, Y. Ozbel, A. Ozbilgin, N, Development of L.tropica-derived exosome-based preventive vaccine against L.tropica induced cutaneous leishmaniasis.. "Molecular Immunology & Immunogenetics Congress III", (2016).
  A.12 B. Gungor, I.C. Ayanoglu, H. Taşkıran, G. Tincer Konig, Y. Ozbel, A. Ozbilgin, N, L.tropica-secreted exosomes as preventive vaccine against L.tropica induced cutaneous leishmaniasis.. "EMBO EMBL Symposia: Innate Immunity in Host Pathogen Interactions,", (2016).
  A.13 Gungor, B.; Ayanoglu, I. C.; Konig, Tincer G. Ozbel Y Ozbilgin A Girginkardesler, Characterization of L. tropica secreted exosomes and development of exosome-based preventive vaccine against L. tropica induced cutaneous leishmaniasis. "EUROPEAN JOURNAL OF IMMUNOLOGY", (2016).

Book and Chapter in a Book

  A.1 Mayda Gursel, D.M.Klinman, Use of CpG oligonucleotides as mucosal adjuvants. "Mucosal Immunology, 4th edition", (2015), p.1201-1210.

Publications (NATIONAL)

 

Conference Papers

  A.1 T. Kahraman, G. Gucluler, M. Gursel, C. Ozen, I. Gursel., Transfer of CpG oligos to cells via exosomes. "21st Turkish Congress of Immunology", (2011).
  A.2 FC. Yagci, O. Aslan, M. Gursel, I. Simsek, B. Bayyurt, I. Gursel, Application of immunsuppressive ODN to treat Autoimmune or Autoinflammatory diseases. "21st National Congress of Immunology", (2011).
  A.3 ; Esin ALPDÜNDAR, Mine ÖZCAN, Fadime KIRAN, Özlem OSMANAĞAOĞLU, İhsan GÜRSEL, Ma, IMMUNOMODULATORY PROPERTIES OF SECRETED MEMBRANE VESICLES DERIVED FROM HUMAN MICROBIOTA. "Molecular Immunology & Immunogenetics Congress (MIMIC2012) Turkish Journal of Immunology Supplement", 17, (2012).
  A.4 Gizem Tincer., Kutay Karatepe, Cevayir Coban, Ken Ishii, Mayda Gursel , Ihsan G, CpG DNA containing nanoparticles as potential antitumor agents. "10th Annual Meeting of the Association for Cancer Immunotherapy", (2012).
  A.5 Bilgi GÜNGÖR, Can ÇOKÇALIŞKAN, Musa ALKAN, Fuat Cem YAĞCI, İhsan GÜRSEL, Mayda G, CPG OLIGODEOXYNUCLEOTIDE/TAT PEPTIDE COMPLEXES ENHANCE THE POTENCY OF FOOT AND MOUTH DISEASE VACCINE IN MICE. "Molecular Immunology & Immunogenetics Congress (MIMIC2012) Turkish Journal of Immunology suppl", 17, (2012).
  A.6 Gizem TINCER, Kutay KARATEPE, Cevayir COBAN, Ken ISHII, Mayda GURSEL, Ihsan GURS, CPG ODN NANOPARTICLES AND POLYSACCHARIDE NANOCOMPLEXES: IMPROVED ANTITUMOR ACTION. "Molecular Immunology & Immunogenetics Congress (MIMIC2012) Turkish Journal of Immunology Supplement", 1, (2012).
  A.7 Fuat Cem YAĞCI, Can ÇOKÇALIŞKAN, Musa ALKAN, Nilüfer ÖZTÜRK, Bilgi GUNGOR, Mayda, USE OF CPG OLIGODEOXYNUCLEOTIDES ENHANCES RAPIDITY, LONGEVITY AND POTENCY OF FMDV VACCINES IN MICE. "Molecular Immunology & Immunogenetics Congress” (MIMIC2012)Turkish Journal of Immunology Suppl", 1, (2012).
  A.8 Bilgi Gungor, Fuat Cem Yagci, Ihsan Gursel, Mayda Gursel, Potentiating the immunostimulatory properties of CpG oligodeoxynucleotides: aiming to develop a better vaccine adjuvant. "10th Annual Meeting of the Association for Cancer Immunotherapy", (2012).
  A.9 Fuat Cem Yagci , Can Cokcaliskan , Musa Alkan , Bilgi Gungor, Mayda Gursel, Ihs, CpG Oligodeoxynucleotides enhances both humoral and cellular immune responses against FMDV in mice. "10th Annual Meeting of the Association for Cancer Immunotherapy", (2012).
  A.10 E.Alpdundar, M.Aydin, S.Yildiz, B.Gungor, M.Ozcan, S.Gunalp, C.Akcali, M.Gursel, Immunomodulatory and Anti –Inflammatory Activities of Commensal Bacteria –Derived Membrane Vesicles. "2nd International Molecular Immunology and Immunogenetics Congress", (2014), s.71.
  A.11 M. Gursel, Vaccine Adjuvant Activity of CpG Oligodeoxynucleotide/Cationic Peptide Nanorings. "2nd International Molecular Immunology and Immunogenetics Congress", (2014), s.21.
  A.12 M.Özcan, B.Güngör, E.Alpdündar, S.Yıldız, B.Bayyurt, G.Güçlüler, I.Gürsel, M.Gür, Differential Activation of Immune Cells by Commensal Versus Pathogen -Derived Bacterial RNA. "2nd International Molecular Immunology and Immunogenetics Congress", (2014), s.46.
  A.13 S.Yildiz, E.Alpdundar, B. Bayyurt, M.Ozcan, G.Gucluler, D.Bayik, B.Gungor, I.Gur, Novel formulations of c-di-GMP enhance its immuno-stimulatory activity. "2nd International Molecular Immunology and Immunogenetics Congress", (2014), s.51.
  A.14 B.Gungor, F.Yagci, I. Ayanoglu, G.Tincer, I.Gursel, M.Gursel, Immunotherapeutic CpG Oligodeoxynucleotide / Cationic Peptide Nanorings as Plasmacytoid Dendritic Cell Stimulators. "2nd International Molecular Immunology and Immunogenetics Congress", (2014), s.77.
  A.15 M Gursel, Bacteria-derived nanovesicles and synthetic CpG containing oligonucleotide/cationic peptide nanorings: applications as immunotherapeutic agents. "NanoTR-11", (2015).
  A.16 E. Alpdundar1 , M. Aydin2 , S. Yildiz1 , C. Akcali3 , I. Gursel2 , M. Gursel1 ;, Commensal bacteria-derived membrane vesicles as novel immunomodulatory therapeutic agents. "4th European Congress of Immunology", (2015).
  A.17 M Gursel, Myd88 Eksikliğinde Sitozolik Patojen Tanıma Reseptörlerinin Rolü. "23. Ulusal Immunoloji Kongresi", (2015).
  A.18 G. Gucluler , T. Kahraman , D. Bayik , M. Gursel , I. Gursel ;, improved immunostimulatory activity of D-type CpG oligonucleotides encapsulated into exosomes in cancer treatment. "4th European Congress of Immunology", (2015).
  A.19 E. Gül, N. Sürücü, B. Güngör, E. Alpdündar, I. Gürsel, M. Gursel, Immün Baskılayıcı Oligodeoksinükleotid A151’in Tip 1 Interferonopatilere Yönelik Terapötik Ajan Olarak Etkileri . "23. Ulusal Immunoloji Kongresi", (2015).
  A.20 B. Gungor1 , M. Gursel1 , &. Gursel2 , G. Tincer Konig2 , F. C. Yagci, CpG ODN/cationic peptide nanorings as anti-viral and anti-tumor agents. "4th European Congress of Immunology", (2015).
  A.21 S.Yildiz , E.Alpdundar , B.Gungor , T.Kahraman , B.Bayyurt , I. Gursel, M.Gursel, Combined use of CpG ODN and CDNs promote synergistic activation in immune cells. "4th European Congress of Immunology", (2015).
  A.22 N. Sürücü1 , E. Gül1 , I. Gursel2 , M. Gursel1 ;, Immunosuppressive effects of synthetic oligodeoxynucleotide A151 on inflammasome activation. "4th European Congress of Immunology", (2015).
  A.23 E. Gül1 , F. K. Eroğlu2 , C. Yakıcıer3 , I. Gürsel4 , S. Özen2 , M. Gürsel1 ;, Type I Interferon Associated Immune Responses In Patients With STING-Associated Vasculopathy With Onset In Infancy. "4th European Congress of Immunology", (2015).
  A.24 T.Kahraman , D.Bayık, F. C.Yağcı, M. Gürsel, İ. Şimşek, A.Dinc, I.Gursel, LL-37 Içeren Hücre Dısı Nano-Keseciklerin Behçet Patogenezindeki Rolleri. "23. Ulusal Immunoloji Kongresi", (2015).
  A.25 az Sürücü , Ersin Gül , İhsan Gürsel , Mayda Gürsel, Immün Baskılayıcı Sentetik Oligodeoksinükleotid A151’in Kontrolsüz Inflamazom Aktivasyonundan Kaynaklı Hastalıklarda Terapötik Ajan Olarak Etkileri . "23. Ulusal Immunoloji Kongresi", (2015).
  A.26 Sinem Günalp, Bilgi Güngör, Esin Alpdündar, Soner Yıldız, Ersin Gül, Mayda Gürse, Kommensal ve Patojen DNA’ larının BağıĢıklık Sistemi Üzerindeki Ġmmünomodulator Etkisi . "23. Ulusal Immunoloji Kongresi", (2015).
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