Assoc.Prof.Dr. ÇAĞDAŞ DEVRİM SON
FACULTY OF ARTS AND SCIENCES
PublicationsResearchMembership & Awards
E-mail :  
Url :  http://www.metu.edu.tr/~cson/
Phone :  +90312210 6472
Fax :  +903122107976
Address :
 

Education

  Bachelor's, Middle East Technical University, Biology
  Master's, Middle East Technical University, Biology
  Doctorate, University of Tennessee, Knoxville, Biochemistry
  Diploma, Middle East Technical University, Chemistry

Publications (INTERNATIONAL)

Journal Papers

  A.1 L. Keith Henry, Sanjay Khare, Cagdas Son, Fred Naider and Jeffrey M. Becker, Identification of a contact region between the tridecapeptide -factor mating pheromone of Saccharomyces cerevisiae and its G protein-coupled receptor by photo-affinity labeling. "Biochemistry", 41, (2001), p.6128-6139.
  A.2 Lee BK, Lee YH, Hauser M, Son CD, Khare S, Naider F, Becker JM., Tyr266 in the sixth transmembrane domain of the yeast -factor receptor plays key roles in receptor activation and ligand specificity. "Biochemistry", 41, (2002), p.13681-13689.
  A.3 Celic, A. ;Martin, N. P. ;Son, C. D. ;Becker, J. M. ;Naider, F. ;Dumont, M. E., Sequences in the intracellular loops of the yeast pheromone receptor Ste2p required for G protein activation. "Biochemistry", 42, (2003), p.3004-3017.
  A.4 Cagdas D. Son, Hasmik Sargsyan, Fred Naider, Jeffrey M. Becker, Identification of binding regions of the Saccharomyces cerevisiae -factor pheromone receptor (Ste2p) by photo-affinity cross-linking. "Biochemistry", 43, (2004), p.13193-13203.
  A.5 Cagdas D. Son, Hasmik Sargsyan, Hurst GB, Fred Naider, Jeffrey M. Becker, Analysis of Ligand-Receptor Cross-linked Fragments by Mass Spectrometry. "Journal of Peptide Research", 65, (2005), p.418-426.
  A.6 BK Lee, K Jung, C Son, H Kim, NC VerBerkmoes, B. Arshava, F. Naider, J.Becker, Affinity purification and Characterization of a G-Protein Coupled Receptor, Saccharomyces cerevisiae Ste2p. "Protein Expression and Purification", 56, (2007), p.62-71.
  A.7 Li-Yin Huang, G. Umanah, M. Hauser, C. Son, B. Arshava, F. Naider and J.Becker, Unnatural amino acid replacement in a yeast G protein-coupled receptor in its native environment. "Biochemistry", 47, (2008), p.5638-5648.
  A.8 Cagdas D. Son, Fraser J. Moss, Bruce N. Cohen, Henry A. Lester, Nicotine Normalizes Intracellular Subunit Stoichiometry of Nicotinic Receptors Carrying Mutations linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy. "Molecular Pharmacology", 75, (2009), p.1137-1148.
  A.9 Lester HA, Xiao C, Srinivasan R, Son CD, Miwa J, Pantoja R, Banghart MR, Dougher, Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry. Implications for Drug Discovery. "AAPS JOURNAL", 11, (2009), p.167-177.
  A.10 George K. E. Umanah, Cagdas Son, FaXiang Ding, Fred Naider and Jeffrey M. Becker, Cross-Linking of a DOPA-Containing Peptide Ligand into Its G Protein-Coupled Receptor. "Biochemistry", 48, (2009), p. 2033-2044.
  A.11 Srinivasan R, Pantoja R, Moss FJ, Mackey ED, Son CD, Miwa J, Lester HA, Nicotine up-regulates {alpha}4{beta}2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning. "J. Gen. Physiol. (JOURNAL OF GENERAL PHYSIOLOGY)", 137(1), (2010), p.59-79.
  A.12 Mehmet Emre Sahin, Tolga Can, and Cagdas Devrim Son, GPCRsort-Responding to the Next Generation Sequencing Data Challenge: Prediction of G protein-coupled receptors classes using Structural region lengths.. "OMICS: A Journal of Integrative Biology", 18, (2014), p.636-44.
 

Conference Papers

  A.1 F. Naider, B. K. Lee, L. K. Henry, Cagdas Son, F. Ding, B. K. Khare, J.M. Becker, Probing The Binding Site Of A Heptahelical Peptide Pheromone Receptor Using Photoaffinity Labeling, Site-Directed Mutagenesis And Spectroscopic Approaches. "2nd International Peptide Symposium in conjunction with the 17th American Peptide Symposium", (2001).
  A.2 Sargsyan, H., Son, C. D., Becker, J. M., and Naider, F, Synthesis and cross-linking of photoactivateable biotinylated ligands of G protein-coupled receptors. "18th American Peptide Symposium", (2003), p.635-636.
  A.3 Cagdas D. Son, Hasmik Sargsyan, Fred Naider, Jeffrey M. Becker, Photo-Affinity Cross-linking of Biotinylated Tridecapeptide Analogs to a G Protein-Coupled Receptor. "The FASEB Journal", 18, (2004).
  A.4 Naider, F., Son, C. A., Sargsyan, H., and Becker, J. M., Biochemical and mutagenic analysis of a G protein-coupled receptor: Photocrosslinking of the tridecapeptide alpha-Factor into Ste2p of Saccharomyces cerevisiae reveals contact points between the peptide and its receptor binding site. "3rd International Peptide Symposium/28th European Peptide Symposium", (2004), p.93-95.
  A.5 George E. Umanah, Cagdas D Son, FaXiang Ding, Fred Naider and Jeffrey M Becker, Cross-Linking of a DOPA-Containing Peptide Ligand into its G Protein-Coupled Receptor. "The FASEB Journal", 23, (2009).
  A.6 Gökhan Ünlü and Çağdaş D. Son, In vivo Detection of Heterodimerization of Two G-protein Coupled Receptors: Dopamine D2r and Adenosine A2AR with FRET Method. "Molecular Pharmacology of G Protein Coupled Receptors and Signalling Partners/ EPHAR", -, (2011), p.30.
  A.7 Gözde Kumaş, Jeffrey M. Becker, and Çağdaş D. Son, Detecting G-protein Coupled Receptor Interactions Using Enhanced Green Fluorescent Protein Reassembly. "11th International ELMI meeting on Advanced Light Miroscopy", -, (2011), p.25.
  A.8 Mehmet Emre Şahin, Tolga Can, and Çağdaş D. Son, Predicting the Interactions between G-Protein Coupled Receptors: Computational and Experimental Approaches. "BeNELux Bioinformatics Conference", -, (2011), p.26.

Translation of a Book or Chapter in a Book

Review of a Book

  A.1 Zeki Kaya, Tolga Can, Yeşim Aydın Son, Çağdaş D. Son..., Büyük ölçekli genomik değişikliklerin tarihsel olarak yeniden yapılandırılması: biyolojik sorular ve hesaplamalı zorluklar. "Biyologlar için Biyoinformatik", (2013), p.359.
  A.2 Çağdaş D. Son, Büyük ölçekli genomik değişikliklerin tarihsel yeniden yapılandırılması: biyolojik sorular ve hesaplamalı zorluklar. "Biyologlar için Biyoenformatik", -, (2014), p.201-224.

Publications (NATIONAL)

 

Conference Papers

  A.1 Cagdas D. Son, Gözde Kumas, Gökhan Unlu, Jeffrey M. Becker, Henry Lester, Decoding Protein-Protein Interactions: What can we do for Membrane Proteins?. "Turkish Journal of Biochemistry", 34, (2009), s.52-53.
  A.2 Çağdaş D. Son, Hasmik Sargsyan, Fred Naider, and Jeffrey M. Becker, Peptit Ligandların G-proteine Kenetli Reseptörler ile Etkileşimleri. "25. Ulusal Kimya Kongresi (Uluslararası katılımlı)", 25, (2011), s.38.
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